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Defeat MSA is an inclusive US based 501(c)(3) charity that aspires to balance efforts to support patients, educate medical professionals, raise public awareness and nurture promising research.

MSA Awareness Month

March is MSA awareness month. This year we are kicking off the month with the 4th Annual #Cake4aCure Campaign.

News from Social Media




MSA Expert Spotlight

Patrik Brundin, M.D., Ph.D.

Patrik Brundin, M.D., Ph.D.

Director, Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan

Dr. Patrik Brundin is one of the top cited researchers in the field of neuroscience with more than 350 publications on Parkinson’s and related diseases such as MSA. He has 35 years of experience studying neurodegenerative diseases, disease pathogenesis and therapeutic neural transplantation into people with Parkinson’s. His current research focuses on pathogenic mechanisms of Parkinson’s and related diseases as well as the development of new therapies that slow or stop disease progression or that repair damaged brain circuits. He was among the first to articulate the “prion-like” hypothesis of Parkinson’s and MSA, which describes how abnormal proteins related to the disease spread from cell to cell in the brain, causing the cellular damage that perpetuates Parkinson’s and Multiple System Atrophy.

List of Publications

Scholia List of Publications

Spotlight Links


about the

MSA Awareness Shoe – #KickMSA

The MSA Awareness Shoe ™ has traveled to dozens of countries, rubbed shoulders with some notable people and visited many famous landmarks. The Shoe is a tool for spreading MSA awareness, increasing support for MSA patients and their caregivers and fighting MSA by raising vital research dollars. It’s journey is undertaken in memory of all those that have died due to MSA and in support of all those presently fighting Multiple System Atrophy!

To date, the Shoe has “Kicked MSA” in a dozen countries across the world. Learn more about the story and the globetrotting journey of the MSA Awareness Shoe. #DefeatMSA #KickMSA

Join the world-wide MSA Awareness initiative

Join the world-wide MSA Awareness initiative


Defeat MSA invites all our friends & allies, around the world, to join us in this noble fight, to speak for those who cannot, with one mind, one heart and one voice: to defeat MSA forever!





The Defeat MSA special Individual Named Legacy Grants program enables donors to fund a scientific research, medical education, patient support or public awareness grant and name it in their own name, in tribute to someone or in memory of a loved one. The Legacy Grants program designates four levels of grants: $15,000 (Platinum), $10,000 (Gold), $5,000 (Silver) and $2,500 (Bronze). MSA research grants begin at the $10,000 level.

Please email: mailto:legacygrants@defeatmsa.org.nz


Caregiver’s Blog

“Are we there yet?..No”- Anne Kastelic (Caregiver, Ohio)

“Are we there yet?..No”- Anne Kastelic (Caregiver, Ohio)

Caregiver Blog Post #2 The road to diagnosis... Are we there yet?...No Now?...No When are we going to get there? Said anyone who has taken a road trip.  Our trip took 3 1/2 years to get a doctor to agree to a diagnosis of "possible/probable MSA" and we were seeing...

Researcher’s Blog

SEMINAR: “A-Syn Conformational Strains and Patient Perspective”

SEMINAR: “A-Syn Conformational Strains and Patient Perspective”

MSA Researcher Raphaella So, PhD candidate (Toronto), and Defeat MSA Patient Advocate Beverly K. Wilson offer some informed insights on Multiple System Atrophy in a recent talk sponsored by our friends at Cure Parkinson’s UK. Beverly’s presentation describes the...

Patient’s Blog

“Defeat MSA is a truly powerful organization, giving voice to those affected by this little known, devastating disease. I have watched this grass roots effort grow since the beginning as a work of love and devotion by its founders. Indescribable grief and suffering has been channeled into positive action to help fund research and provide support for others dealing with MSA. It is an important and worthwhile organization and I hope to see it continue to grow and prosper.”

Elena Fracassa, MS

“I have observed this charity grow since it’s inception. The charity remains true to its objective of supporting patients and families living with this dreadful disease, through support groups, loaner equipment through the loaner closet program, networking on social media to connect families sharing their experiences across the world. This disease does not have a marathon or a 5k run in its name; the charity uses an intriguing device: a shoe as a symbolic marathon to spread awareness among lay public about this devastating disease. “

Dr. Pratik Bhattacharya, MD, MPH

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